Defeat Diabetes has commissioned a clinical research study on how the use of a smartphone app can help patients manage their type 2 diabetes. La Trobe University is investigating the effects of using the Defeat Diabetes app to implement a low carb diet and lifestyle changes to improve glycaemic control over a 12-month period.
The participants are nominated by their GPs, who also review changes to their bio-markers over the course of the research period. Below is the case study of research participant Mr B.
Background
- Male 34 years old
- Sedentary office worker
- New diagnosis T2DM, strong family history
- Hispanic background
- Currently on no medications
- Asymptomatic – abnormal glucose tests picked up on hospital a admission for renal colic
- Marked ‘Fatty Liver” on discharge
Management options for Mr B: Lifestyle and/or medications
- Lifestyle
- Traditional dietary approach
- Offer remission via Defeat Diabetes low carb approach
- Medication
- Metformin
- ? Dual therapy
- How do we decide?
Progress over time
- Achieved T2D remission without prescribed medication
- Highly motivated due to a strong family history of T2D
- Received low carbohydrate dietary advice from GP at diagnosis
- Support provided from a friend who was familiar with ketogenic diet
Outcome Measure | Jan 22 | May 22 | Oct 22 |
|---|---|---|---|
Fasting Blood Glucose mmol/L | 13.8 | 6.5 | 4.6 |
Haemoglobin A1c % | 8.0 | 4.6 | 4.6 |
Total Cholesterol mmol/L | 4.6 | 4.7 | - |
LDL mmol/L | - | 2.9 | - |
Triglycerides mmol/L | 6.6 | 1.76 | 1.1 |
eGFR | >90 | >90 | - |
ALT U/L | 33 | - | 12 |
GGT U/L | 58 | - | 32 |
hs-CRP | - | - | - |
BP mmHg | 153/101 | 143/100 | 127/89 |
Weight Kg | 81.8 | 78.9 | 75 |
Waist circumference cm | 93 | - | 77 |
Height | 165.5 | - | - |
BMI | 29.9 | 28.8 | 27.3 |