Defeat Diabetes

< 1 min read

Defeat Diabetes has commissioned a clinical research study on how the use of a smartphone app can help patients manage their type 2 diabetes. La Trobe University is investigating the effects of using the Defeat Diabetes app to implement a low carb diet and lifestyle changes to improve glycaemic control over a 12-month period.

The participants are nominated by their GPs, who also monitor their bio-markers over the course of the research period.  Below is the case study of research participant Mr D. 

 

Background

  • Male 72 years old
  • Retired teacher
  • Caucasian background
  • Type 2 diabetes diagnosed in 2005
  • Other medical history: Hypertension, coronary artery disease requiring stenting 2005, renal impairment due to NSAID injury 2016, gastro-oesophageal reflux disease 2021
  • Medications: Cartia 100mg daily, Empagliflozin/Metformin 5/500mg one daily, Semaglutide 1mg SC weekly Rosuvastatin 10mg daily, Ezetimide 10mg daily, Telmisartan 40mg daily, Esomeprazole 20mg daily

Started on LCHF diet on 9/2/23 as diabetes was poorly controlled and had not been able to get a supply of semaglutide on a regular basis. Empaglifolazin was ceased on initiation of LCHF diet.

Over the next 6 months, the following medication was de-prescribed on review: 

  • Telmisartan reduced to 40mg daily and likely to cease on the next review
  • Esomeprazole 20mg daily ceased – GORD has resolved
  • Ezetimide 10mg daily ceased – cholesterol was well within targets ranges
  • Semaglutide 1mg SC weekly- unavailable

Outcome Measure

May 20 2023

April 4 2023

July 4 2023

Fasting Blood Glucose mmol/L

18.4

12.4

7.2

Haemoglobin A1c %

9.3

7.1

6.0

Total Cholesterol mmol/L

2.5

2.2

2.2

Trig

1.6

-

1.0

GFR

33

42

57

ALT

23

28

26

GGT

31

24

20

BP

112/69

123/67

102/78

Wt

80.1 kg

79 kg

74.7 kg

Waist circumference cm

103 cm

102 cm

100 cm

BMI

27.6

7.2

25.7

Summarising the main benefits:

  • Improved HBA1C
  • Improved GFR
  • Weight loss
  • 4 Medications ceased and money saved!

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